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Article

Ikaros, Aiolos and Helios: Transcription regulators and lymphoid malignancies

20 May 2003

Abstract excerpt

Ikaros, Aiolos and Helios encode zinc finger transcription factors that are important regulators of lymphoid development and differentiation. These proteins are involved in the control of gene expression and when associated with nuclear complexes, participate in nucleosome remodeling. Because differential splicing produces multiple protein isoforms with potentially different functions, the Ikaros protein family...

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Identifiers

PMID: 12752680
DOI: 10.1046/j.1440-1711.2003.01159.x

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