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Rapid and reliable screening of HLA-B*15:02 in four Chinese populations using single-tube multiplex real-time PCR assay.

Pharmacogenomics - 1 Jun 2017

Wang Huijuan, Kang Xing, Zhou Shaohe, Chen Rong, Liu Zhengbin, Han Min, Chen Chao, Gong Yongkuan

Abstract excerpt

AIM: HLA-B*15:02 screening should be performed to prevent antiepileptic drug induced severe cutaneous adverse reactions in populations of Asian origin. This study aimed to develop fast and reliable HLA-B*15:02 genotyping method and to investigate the distribution of HLA-B*15:02 in different Chinese ethnicities. MATERIALS & METHODS: A single-tube multiplex real-time PCR assay for HLA-B*15:02 genotyping was...

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PMID: 28594280
DOI: 10.2217/pgs-2017-0041

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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