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Article

Effects of the BDNF Val66Met Polymorphism on Anxiety-Like Behavior Following Nicotine Withdrawal in Mice.

Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco - 1 Dec 2015

Lee Bridgin G, Anastasia Agustin, Hempstead Barbara L, Lee Francis S, Blendy Julie A

Abstract excerpt

INTRODUCTION: Nicotine withdrawal is characterized by both affective and cognitive symptoms. Identifying genetic polymorphisms that could affect the symptoms associated with nicotine withdrawal are important in predicting withdrawal sensitivity and identifying personalized cessation therapies. In the current study we used a mouse model of a non-synonymous single nucleotide polymorphism in the translated region of...

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Source

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Identifiers

PMID: 25744957
DOI: 10.1093/ntr/ntv047
PMCID: PMC4654761

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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