Further evidence for the association of the NPSR1 gene A/T polymorphism (Asn107Ile) with impulsivity and hyperactivity.

doi:10.1177/0269881115573803

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Article

Further evidence for the association of the NPSR1 gene A/T polymorphism (Asn107Ile) with impulsivity and hyperactivity.

Journal of psychopharmacology (Oxford, England) - 1 Aug 2015

Laas Kariina, Eensoo Diva, Paaver Marika, Lesch Klaus-Peter, Reif Andreas, Harro Jaanus

Abstract excerpt

Administration of neuropeptide S (NPS) elicits anxiolysis, arousal and higher activity in rodents. In humans, the NPS receptor (NPSR1) gene rs324981 A/T (Asn(107)Ile) polymorphism is associated with fear responses and anxiety. We have recently revealed an association of NPSR1 with impulsivity-related traits and psychopathology. In the present study the association of the NPSR1 genotype with impulsivity and...

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Identifiers

PMID: 25744621
DOI: 10.1177/0269881115573803

Genes

NPSR1
NPS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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