Significant association between the C(-1019)G functional polymorphism of the HTR1A gene and impulsivity.

doi:10.1002/ajmg.b.31025

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Article

Significant association between the C(-1019)G functional polymorphism of the HTR1A gene and impulsivity.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Mar 2010

Benko Anita, Lazary Judit, Molnar Eszter, Gonda Xenia, Tothfalusi Laszlo, Pap Dorottya, Mirnics Zsuzsanna, Kurimay Tamas, Chase Diana, Juhasz Gabriella, Anderson Ian M, Deakin John F W, Bagdy Gyorgy

Abstract excerpt

Serotonin-1A (5-HT(1A)) receptors are known to play a role in impulsivity-related behavior. The C(-1019)G functional polymorphism (rs6295) has been suggested to regulate the 5-HT(1A) receptor gene (HTR(1A)) expression in presynaptic raphe neurons, namely, increased receptor concentration and redu...

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PMID: 19725031
DOI: 10.1002/ajmg.b.31025

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19725031-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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