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Article

Conserved and divergent aspects of human T-cell development and migration in humanized mice.

Immunology and cell biology - 1 Sept 2015

Halkias Joanna, Yen Bonnie, Taylor Kayleigh T, Reinhartz Olaf, Winoto Astar, Robey Ellen A, Melichar Heather J

Abstract excerpt

Humanized mice represent an important model to study the development and function of the human immune system. While it is known that mouse thymic stromal cells can support human T-cell development, the extent of interspecies cross-talk and the degree to which these systems recapitulate normal human T-cell development remain unclear. To address these questions, we compared conventional and non-conventional T-cell...

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Identifiers

PMID: 25744551
DOI: 10.1038/icb.2015.38
PMCID: PMC4575952

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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