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Article

The DREAM complex promotes gene body H2A.Z for target repression.

Genes & development - 1 Mar 2015

Latorre Isabel, Chesney Michael A, Garrigues Jacob M, Stempor Przemyslaw, Appert Alex, Francesconi Mirko, Strome Susan, Ahringer Julie

Abstract excerpt

The DREAM (DP, Retinoblastoma [Rb]-like, E2F, and MuvB) complex controls cellular quiescence by repressing cell cycle genes, but its mechanism of action is poorly understood. Here we show that Caenorhabditis elegans DREAM targets have an unusual pattern of high gene body HTZ-1/H2A.Z. In mutants of lin-35, the sole p130/Rb-like gene in C. elegans, DREAM targets have reduced gene body HTZ-1/H2A.Z and increased...

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Identifiers

PMID: 25737279
DOI: 10.1101/gad.255810.114
PMCID: PMC4358402

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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