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Article

DREAM interrupted: severing LIN-35-MuvB association in Caenorhabditis elegans impairs DREAM function but not its chromatin localization.

Genetics - 4 Jul 2022

Goetsch Paul D, Strome Susan

Abstract excerpt

The mammalian pocket protein family, which includes the Retinoblastoma protein (pRb) and Rb-like pocket proteins p107 and p130, regulates entry into and exit from the cell cycle by repressing cell cycle gene expression. Although pRb plays a dominant role in mammalian systems, p107 and p130 are the ancestral pocket proteins. The Rb-like pocket proteins interact with the highly conserved 5-subunit MuvB complex and...

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PMID: 35554539
DOI: 10.1093/genetics/iyac073
PMCID: PMC9252284

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DREAM interrupted: severing LIN-35-MuvB association in Caenorhabditis elegans impairs DREAM function but not its chromatin localization.PMID 35554539Read ↗

DREAM Interrupted: Severing LIN-35-MuvB association in <i>Caenorhabditis elegans</i> impairs DREAM function but not its chromatin localizationSemantic proximity Read ↗

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