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Article

Implications of HLA-E allele expression and different HLA-E ligand diversity for the regulation of NK cells.

Human immunology - 1 Nov 2000

Maier S, Grzeschik M, Weiss E H, Ulbrecht M

Abstract excerpt

The interaction of HLA-E with CD94/NKG2A is dependant on the binding of HLA class I signal sequence derived peptides to HLA-E. In the caucasoid population two HLA-E alleles are observed at equal frequencies. Here we study the functional differences between the two HLA-E molecules with regard to cell surface expression, peptide binding, and potential to inhibit lytic activity of a CD94/NKG2A(+) NK cell line. In...

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Source

Identifiers

PMID: 11137208
DOI: 10.1016/s0198-8859(00)00190-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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