Article
A thymine-adenine dinucleotide repeat polymorphism near IL28B is associated with spontaneous clearance of hepatitis C virus.
Journal of gastroenterology - 1 Oct 2015
Hiramine Satoshi, Sugiyama Masaya, Furusyo Norihiro, Uto Hirofumi, Ido Akio, Tsubouchi Hirohito, Watanabe Hisayoshi, Ueno Yoshiyuki, Korenaga Masaaki, Murata Kazumoto, Masaki Naohiko, Hayashi Jun, Thomas David L, Mizokami Masashi
Abstract excerpt
BACKGROUND: Genome-wide association studies have revealed several single-nucleotide polymorphisms around interleukin 28B (IL28B) that are strongly associated with hepatitis C virus (HCV) clearance. However, their predictive value is not perfect, which suggests that other genetic factors may also be involved in HCV clearance. We previously reported a wide variation in the length of a thymine-adenine (TA)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
