Article
IL28B genetic variation is associated with spontaneous clearance of hepatitis C virus, treatment response, serum IL-28B levels in Chinese population.
PloS one - 1 Jan 2012
Shi Xiaodong, Pan Yu, Wang Moli, Wang Dongsheng, Li Wanyu, Jiang Tao, Zhang Peng, Chi Xiumei, Jiang Yanfang, Gao Yanhang, Zhong Jin, Sun Bing, Xu Damo, Jiang Jing, Niu Junqi
Abstract excerpt
BACKGROUND: The interleukin-28B gene (IL28B) locus has been associated with host resistance to hepatitis C virus (HCV) infection and response to PEG-IFN/RBV treatment in western populations. This study was to determine whether this gene variant is also associated with spontaneous clearance of HCV infection, treatment response and IL-28B protein production in Chinese patients. METHODS: We genotyped IL28B genetic...
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