Article
Meta-analysis: implications of interleukin-28B polymorphisms in spontaneous and treatment-related clearance for patients with hepatitis C.
BMC medicine - 8 Jan 2013
Jiménez-Sousa María A, Fernández-Rodríguez Amanda, Guzmán-Fulgencio María, García-Álvarez Mónica, Resino Salvador
Abstract excerpt
BACKGROUND: Since 2009, several studies have identified single-nucleotide polymorphisms (SNPs) near the gene encoding for interleukin (IL)-28 (IL28B) that are strongly associated with spontaneous and treatment-induced hepatitis C virus (HCV) clearance. Because this large amount of data includes some inconsistencies, we consider assessment of the global estimate for each SNP to be essential. METHODS: Relevant...
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