Article
Interleukin-28B genetic variations and spontaneous clearance of hepatitis C antibody-positive blood donors in China.
Transfusion - 1 Oct 2013
Liu Yu, Ma Hongli, Chen Shanhua, Wang Jingxing, Liu Gui, Xu Min, Ke Ling, He Miao
Abstract excerpt
BACKGROUND: Single-nucleotide polymorphisms (SNPs) near the interleukin (IL)28B gene have been shown to be associated with spontaneous clearance of hepatitis C virus (HCV) infection in western populations. Anti-HCV-reactive and HCV RNA-negative samples were often found in Chinese blood donors. This study was to determine whether the IL28B gene variant is also associated with the natural outcome of HCV infection...
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