Article
Polymorphisms near interleukin 28B gene are not associated with hepatitis B virus clearance, hepatitis B e antigen clearance and hepatocellular carcinoma occurrence.
Intervirology - 1 Jan 2013
Lee Dong Hyeon, Cho Yuri, Seo Ji Yeon, Kwon Jung Hee, Cho Eun Ju, Jang Eun Sun, Kwak Min-Sun, Cheong Jae Youn, Cho Sung Won, Lee Jeong-Hoon, Yu Su Jong, Yoon Jung-Hwan, Lee Hyo-Suk, Kim Chung Yong, Shin Hyoung Doo, Kim Yoon Jun
Abstract excerpt
BACKGROUND: Polymorphisms near the IL28B gene have been proposed to be strongly associated with treatment response and the rate of spontaneous clearance of hepatitis C virus infection, and treatment response of hepatitis B virus (HBV) infection. In this study, we aimed to determine whether these polymorphisms could affect natural courses of HBV infection. METHODS: Genetic variations were identified through direct...
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