Article
Integrative molecular profiling of routine clinical prostate cancer specimens.
Annals of oncology : official journal of the European Society for Medical Oncology - 1 Jun 2015
Grasso C S, Cani A K, Hovelson D H, Quist M J, Douville N J, Yadati V, Amin A M, Nelson P S, Betz B L, Liu C-J, Knudsen K E, Cooney K A, Feng F Y, McDaniel A S, Tomlins S A
Abstract excerpt
BACKGROUND: Comprehensive molecular profiling led to the recognition of multiple prostate cancer (PCa) molecular subtypes and driving alterations, but translating these findings to clinical practice is challenging. PATIENTS AND METHODS: We developed a formalin-fixed paraffin-embedded (FFPE) tissue compatible integrative assay for PCa molecular subtyping and interrogation of relevant genetic/transcriptomic...
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