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Article

Patterns of structural variation define prostate cancer across disease states

9 Aug 2022

Abstract excerpt

The complex genomic landscape of prostate cancer evolves across disease states under therapeutic pressure directed toward inhibiting androgen receptor (AR) signaling. While significantly altered genes in prostate cancer have been extensively defined, there have been fewer systematic analyses of how structural variation shapes the genomic landscape of this disease across disease states. We uniformly characterized...

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Identifiers

PMID: 35943799
DOI: 10.1172/jci.insight.161370

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