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Article

Protected DNA strand displacement for enhanced single nucleotide discrimination in double-stranded DNA.

Scientific reports - 4 Mar 2015

Khodakov Dmitriy A, Khodakova Anastasia S, Huang David M, Linacre Adrian, Ellis Amanda V

Abstract excerpt

Single nucleotide polymorphisms (SNPs) are a prime source of genetic diversity. Discriminating between different SNPs provides an enormous leap towards the better understanding of the uniqueness of biological systems. Here we report on a new approach for SNP discrimination using toehold-mediated DNA strand displacement. The distinctiveness of the approach is based on the combination of both 3- and 4-way branch...

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Identifiers

PMID: 25735213
DOI: 10.1038/srep08721
PMCID: PMC4348642

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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