Article
Discrimination of single nucleotide polymorphisms by strand exchange assay using partially double-stranded probes.
Nucleic acids symposium series (2004) - 1 Jan 2005
Hirata Kazuya, Ishii Daisuke, Kano Arihiro, Yamayoshi Asako, Akaike Toshihiro, Maruyama Atsushi
Abstract excerpt
Previously we designed the partially double-stranded (PDS) probes that have protruding single-stranded portion for a single-base mismatch analysis. The single-stranded portion is engineered to sense existences of mismatches in the counterparts and to transduce it in strand exchange rates. Here we...
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