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Article

Mitochondrial Copy Number is Associated with Colorectal Cancer Risk

1 Sept 2012

Abstract excerpt

BACKGROUND: Mitochondria are eukaryotic organelles responsible for energy production. Quantitative changes in human mitochondrial DNA (mtDNA) copy number have been implicated in various cancer types. Data from prospective cohort studies on mtDNA copy number and colorectal cancer risk have been lacking. METHODS: We evaluated the association between mtDNA copy number in peripheral blood and colorectal cancer risk...

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PMID: 22787200
DOI: 10.1158/1055-9965.epi-12-0138-t

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