Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Frequent somatic mutations of mitochondrial DNA in traditional serrated adenomas but not in sessile serrated adenomas of the colorectum.

Journal of gastroenterology and hepatology - 1 Oct 2011

Shimomura Takako, Hiyama Toru, Oka Shiro, Tanaka Shinji, Yoshihara Masaharu, Shimamoto Fumio, Chayama Kazuaki

Abstract excerpt

BACKGROUND AND AIM: Serrated adenomas (SAs), recently subdivided into traditional SAs (TSAs) and sessile SAs (SSAs), are recognized as a distinct form of neoplasia of the colorectum. One of the characteristics of SAs is hypermaturation of the gland epithelium due to the low extent of cell loss by apoptosis. Mutations of mitochondrial DNA (mtDNA) are closely associated with abnormality in apoptosis. We therefore...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenoma
Share to Biomarkers, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma

Share to Colonic Polyps

Share to Colorectal Neoplasms

Share to DNA, Mitochondrial

Share to Hyperplasia

Source

Identifiers

PMID: 21649722
DOI: 10.1111/j.1440-1746.2011.06797.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Frequent somatic mutations of mitochondrial DNA in traditional serrated adenomas but not in sessile serrated adenomas of the colorectum.PMID 21649722Read ↗

Clinical features and molecular alterations of traditional serrated adenoma in sporadic colorectal carcinogenesis.Semantic proximity Read ↗

Genetic characteristics of mitochondrial DNA was associated with colorectal carcinogenesis and its prognosis.Semantic proximity Read ↗

Is cumulative frequency of mitochondrial DNA variants a biomarker for colorectal tumor progression?Semantic proximity Read ↗

My approach to serrated polyps of the colorectumSemantic proximity Read ↗

KRAS mutations in traditional serrated adenomas from Korea herald an aggressive phenotype.Semantic proximity Read ↗

Serrated and non-serrated polyps of the colorectum: their prevalence in an unselected case series and correlation of BRAF mutation analysis with the diagnosis of sessile serrated adenoma.Semantic proximity Read ↗

Frequent p53 gene mutations in serrated adenomas of the colorectum.Semantic proximity Read ↗

Clinicopathologic and genetic characterization of traditional serrated adenomas of the colon.Semantic proximity Read ↗

BRAF mutation is associated with the unique morphology of traditional serrated adenoma of the colorectum.Semantic proximity Read ↗

[BRAF mutation in colorectal serrated lesions].Semantic proximity Read ↗

Mitochondrial DNA mutations in oxyphilic and chief cell parathyroid adenomasSemantic proximity Read ↗

Analysis of mtDNA sequence variants in colorectal adenomatous polyps.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.