Article
[The relationship between copy number and microsatellite instability of mitochondrial DNA in colorectal cancer].
Zhonghua nei ke za zhi - 1 Oct 2009
Huang Ping, Zhang Yun-xin, Zhao Ting
Abstract excerpt
OBJECTIVE: To study the relationship between the abnormality of mitochondrial DNA (mtDNA) copy number and the clinical parameters and microsatellite instability (MSI) in colorectal cancer. METHODS: Total DNA was extracted from cancer and pericancer tissue from 50 colorectal cancer (CRC) biopsy samples. Non-coding region sequencing was done and the copy number of mtDNA was quantitated with real-time PCR in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
