Article
Association of mitochondrial copy number variation and T16189C polymorphism with colorectal cancer in North Indian population.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Nov 2017
Kumar Bhupender, Bhat Zafar Iqbal, Bansal Savita, Saini Sunil, Naseem Afreen, Wahabi Khushnuma, Burman Archana, Kumar Geeta Trilok, Saluja Sundeep Singh, Rizvi M Moshahid Alam
Abstract excerpt
Globally, colorectal cancer is the third most common type of cancer. Genetic instability leading to cancer development is one of the major causes for development of cancer. Alterations in mitochondrial genome, that is, mutations, single-nucleotide polymorphisms, and copy number variations are known to contribute in cancer development. The aim of our study was to investigate association of mitochondrial T16189C...
Topics
- Adult
- Aged
- Asian People
- Colorectal Neoplasms
- DNA Copy Number Variations
- DNA, Mitochondrial
- Female
- Genetic Predisposition to Disease
- Genotype