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Article

Bayesian multivariant fine mapping using the Laplace prior.

Genetic epidemiology - 1 Apr 2023

Walters Kevin, Yaacob Hannuun

Abstract excerpt

Currently, the only effect size prior that is routinely implemented in a Bayesian fine-mapping multi-single-nucleotide polymorphism (SNP) analysis is the Gaussian prior. Here, we show how the Laplace prior can be deployed in Bayesian multi-SNP fine mapping studies. We compare the ranking performance of the posterior inclusion probability (PIP) using a Laplace prior with the ranking performance of the...

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PMID: 36739616
DOI: 10.1002/gepi.22517

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