Article
Incorporating prior knowledge to increase the power of genome-wide association studies.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2013
Petersen Ashley, Spratt Justin, Tintle Nathan L
Abstract excerpt
Typical methods of analyzing genome-wide single nucleotide variant (SNV) data in cases and controls involve testing each variant's genotypes separately for phenotype association, and then using a substantial multiple-testing penalty to minimize the rate of false positives. This approach, however,...
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