Article
The analysis of a large Danish family supports the presence of a susceptibility locus for adenoma and colorectal cancer on chromosome 11q24.
Familial cancer - 1 Sept 2015
Rudkjøbing Laura Aviaja, Eiberg Hans, Mikkelsen Hanne Birte, Binderup Marie Louise Mølgaard, Bisgaard Marie Luise
Abstract excerpt
Hereditary colorectal cancer accounts for approximately 30% of all colorectal cancers, but currently only 5% of these families can be explained by highly penetrant, inherited mutations. In the remaining 25% it is not possible to perform a gene test to identify the family members who would benefit from prophylactic screening. Consequently, all family members are asked to follow a screening program. The purpose of...
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