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Article

A role for matrix stiffness in the regulation of cardiac side population cell function.

American journal of physiology. Heart and circulatory physiology - 1 May 2015

Qiu Yiling, Bayomy Ahmad F, Gomez Marcus V, Bauer Michael, Du Ping, Yang Yanfei, Zhang Xin, Liao Ronglih

Abstract excerpt

The mechanical properties of the local microenvironment may have important influence on the fate and function of adult tissue progenitor cells, altering the regenerative process. This is particularly critical following a myocardial infarction, in which the normal, compliant myocardial tissue is replaced with fibrotic, stiff scar tissue. In this study, we examined the effects of matrix stiffness on adult cardiac...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25724498
DOI: 10.1152/ajpheart.00935.2014
PMCID: PMC4551131

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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