Article
Gene polymorphisms, tobacco exposure and oral cancer susceptibility: a study from Gujarat, West India.
Oral diseases - 1 Jan 2014
Singh R D, Haridas N, Shah F D, Patel J B, Shukla S N, Patel P S
Abstract excerpt
Polymorphic variability in the enzymes involved in biotransformation of tobacco-related pro-carcinogens plays an important role in modulating oral cancer susceptibility. CYP1A1*2A, CYP1A1*2C, GSTM1 and GSTT1 polymorphisms were determined in 122 oral carcinoma cases and 127 controls from Gujarat, West India using PCR-based methods. The results revealed that the polymorphic variants of CYP1A1 gene did not show...
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