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Article

Interaction of αA-crystallin F71L mutant with wild type αA- and αB-crystallins by mammalian two hybrid assay.

International journal of biological macromolecules - 1 May 2015

Ramkumar Srinivasagan, Thankappan Bency, Fujii Noriko, Natarajaseenivasan Kalimuthusamy, Anbarasu Kumarasamy

Abstract excerpt

Incidence of age related cataract (ARC) increases by a variety of factors including metabolic and environmental factors. Nonetheless, genetic mutations are responsible for the altered structural stability of the proteins, especially; the F71L mutation in αA-crystallin has been shown to be responsible for the incidence of cataracts. However, structural characteristics and chaperone function of this mutant and its...

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Source

Identifiers

PMID: 25720831
DOI: 10.1016/j.ijbiomac.2015.02.025

Genes

ARC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Interaction of αA-crystallin F71L mutant with wild type αA- and αB-crystallins by mammalian two hybrid assay.PMID 25720831Read ↗

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