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Structural and functional analysis of SNP rs76740365 G>A in exon-3 of alpha A-crystallin gene in lens epithelial cells

2022-03-03

Abstract excerpt

Age-related cataract (ARC) is the leading cause of visual impairment and blindness worldwide among older adults. As a major structural protein in lens, alpha A-crystallin (CRYAA) plays a crucial role in maintaining lens transparency. Previously, we have identified a single nucleotide polymorphism in the exon-3 of CRYAA gene associated with the susceptibility of ARC, especially posterior subcapsular cataract. To cl...

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Literature Corpus work
84f8f31e-9d67-54ec-afbc-e4aa8bb9e8cb
DOI
10.21203/rs.3.rs-1399398/v1
Open publication

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Structural and functional analysis of SNP rs76740365 G>A in exon-3 of alpha A-crystallin gene in lens epithelial cellsDOI 10.21203/rs.3.rs-1399398/v1
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