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Article

Differential role of arginine mutations on the structure and functions of α-crystallin.

Biochimica et biophysica acta - 1 Jan 2016

Panda Alok Kumar, Nandi Sandip Kumar, Chakraborty Ayon, Nagaraj Ram H, Biswas Ashis

Abstract excerpt

BACKGROUND: α-Crystallin is a major protein of the eye lens in vertebrates. It is composed of two subunits, αA- and αB-crystallin. α-Crystallin is an oligomeric protein having these two subunits in 3:1 ratio. It belongs to small heat shock protein family and exhibits molecular chaperone function, which plays an important role in maintaining the lens transparency. Apart from chaperone function, both subunits also...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26080000
DOI: 10.1016/j.bbagen.2015.06.004
PMCID: PMC4914040

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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