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Article

Joint effect of ADARB1 gene, HTR2C gene and stressful life events on suicide attempt risk in patients with major psychiatric disorders.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry - 1 Jun 2015

Karanović Jelena, Šviković Saša, Pantović Maja, Durica Svetlana, Brajušković Goran, Damjanović Aleksandar, Jovanović Vladimir, Ivković Maja, Romac Stanka, Savić Pavićević Dušanka

Abstract excerpt

OBJECTIVES: Adenosine to inosine RNA editing, serotonin 2C receptor (HTR2C), and stressful life events (SLEs) have all been implicated in suicidal behaviour. We examined the main and moderating effects of RNA editing (ADAR, ADARB1) and HTR2C genes, childhood trauma (CT), recent SLEs and psychiatric disorders as contributors to suicide attempt (SA) vulnerability. METHODS: Study included 165 suicide attempters and...

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Share to Adenosine Deaminase
Share to Bipolar Disorder

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Depressive Disorder, Major

Share to Life Change Events

Share to Receptor, Serotonin, 5-HT2C

Share to RNA Editing

Share to Suicide, Attempted

Share to Tomography, X-Ray Computed

Source

Identifiers

PMID: 25732952
DOI: 10.3109/15622975.2014.1000374

Genes

ADARB1
ADAR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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