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Article

The putative tumor suppressor gene EphA3 fails to demonstrate a crucial role in murine lung tumorigenesis or morphogenesis.

Disease models & mechanisms - 1 Apr 2015

Lahtela Jenni, Pradhan Barun, Närhi Katja, Hemmes Annabrita, Särkioja Merja, Kovanen Panu E, Brown Arthur, Verschuren Emmy W

Abstract excerpt

Treatment of non-small cell lung cancer (NSCLC) is based on histological analysis and molecular profiling of targetable driver oncogenes. Therapeutic responses are further defined by the landscape of passenger mutations, or loss of tumor suppressor genes. We report here a thorough study to addres...

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Source

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Identifiers

PMID: 25713296
DOI: 10.1242/dmm.019257
PMCID: PMC4381338

Genes

EPHA3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25713296-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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