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Article

Effects of cancer-associated EPHA3 mutations on lung cancer.

Journal of the National Cancer Institute - 8 Aug 2012

Zhuang Guanglei, Song Wenqiang, Amato Katherine, Hwang Yoonha, Lee Keunwook, Boothby Mark, Ye Fei, Guo Yan, Shyr Yu, Lin Luping, Carbone David P, Brantley-Sieders Dana M, Chen Jin

Abstract excerpt

BACKGROUND: Cancer genome sequencing efforts recently identified EPHA3, which encodes the EPHA3 receptor tyrosine kinase, as one of the most frequently mutated genes in lung cancer. Although receptor tyrosine kinase mutations often drive oncogenic conversion and tumorigenesis, the oncogenic poten...

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Source

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Identifiers

PMID: 22829656
DOI: 10.1093/jnci/djs297
PMCID: PMC3611812

Genes

EPHA3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22829656-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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