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Article

Recurrent genomic rearrangements in primary testicular lymphoma

25 Feb 2015

Abstract excerpt

Primary testicular diffuse large B cell lymphoma (PTL) is an aggressive malignancy that occurs in the immune-privileged anatomical site of the testis. We have previously shown that structural genomic rearrangements involving the MHC class II transactivator CIITA and programmed death ligands (PDLs) 1 and 2 are frequent across multiple B cell lymphoma entities. Specifically in PTL, we found rearrangements in the...

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PMID: 25712539
DOI: 10.1002/path.4522

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