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Article

Genomic alterations of the JAK2 and PDL loci occur in a broad spectrum of lymphoid malignancies.

Genes, chromosomes & cancer - 1 May 2016

Van Roosbroeck Katrien, Ferreiro Julio Finalet, Tousseyn Thomas, van der Krogt Jo-Anne, Michaux Lucienne, Pienkowska-Grela Barbara, Theate Ivan, De Paepe Pascale, Dierickx Daan, Doyen Chantal, Put Natalie, Cools Jan, Vandenberghe Peter, Wlodarska Iwona

Abstract excerpt

The recurrent 9p24.1 aberrations in lymphoid malignancies potentially involving four cancer-related and druggable genes (JAK2, CD274/PDL1, PDCD1LG2/PDL2, and KDM4C/JMJD2Cl) are incompletely characterized. To gain more insight into the anatomy of these abnormalities, at first we studied 9p24.1 alterations in 18 leukemia/lymphoma cases using cytogenetic and molecular techniques. The aberrations comprised structural...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26850007
DOI: 10.1002/gcc.22345

Genes

JAK2
IGH
CIITA
IGL
PHACTR4
RANBP6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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