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Article

Structural genomic alterations in primary mediastinal large B-cell lymphoma.

Leukemia & lymphoma - 1 Jan 2015

Twa David D W, Steidl Christian

Abstract excerpt

Primary mediastinal large B-cell lymphoma (PMBCL) is an aggressive non-Hodgkin lymphoma that displays phenotypic and genotypic similarity to Hodgkin lymphoma and diffuse large B-cell lymphoma. Studies using genome-wide discovery tools have revealed specific, recurrent structural aberrations as critical somatic events in the pathogenesis of PMBCL. These structural alterations prominently include transcript and...

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Share to Cell Transformation, Neoplastic
Share to Chromosome Aberrations
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genome, Human

Share to Genomics

Share to Lymphoma, Large B-Cell, Diffuse

Share to Mediastinal Neoplasms

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Source

Identifiers

PMID: 25393674
DOI: 10.3109/10428194.2014.985673

Genes

JAK2
CIITA
REL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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