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Article

Differential requirements for β-catenin in murine prostate cancer originating from basal versus luminal cells.

The Journal of pathology - 1 Jul 2015

Lu Tsai-Ling, Chen Chun-Ming

Abstract excerpt

A driver mutation occurring in different cells of origin may impact cancer progression differently. Previously, we demonstrated higher invasiveness in Pten-deficient prostate cancer (CaP) arising from basal cells compared to that arising from luminal cells in mice. Here, we show higher expression of epithelial-mesenchymal transition (EMT)-inducing transcription factors and stem/progenitor properties in...

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Identifiers

PMID: 25712462
DOI: 10.1002/path.4521

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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