Article
Cell types of origin for prostate cancer.
Current opinion in cell biology - 1 Dec 2015
Lee Suk Hyung, Shen Michael M
Abstract excerpt
Analyses of cell types of origin for prostate cancer should result in new insights into mechanisms of tumor initiation, and may lead to improved prognosis and selection of appropriate therapies. Here, we review studies using a range of methodologies to investigate the cell of origin for mouse and human prostate cancer. Notably, analyses using tissue recombination assays support basal epithelial cells as a cell of...
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