Article
Prognostic significance of high circulating sHLA-G in ovarian carcinoma.
HLA - 1 Oct 2021
Babay Wafa, Boujelbene Nadia, Ben Yahia Hamza, Bortolotti Daria, Zemni Ines, Ouzari Hadda-Imene, Chelbi Hanene, Mezlini Amel, Rizzo Roberta, Zidi Inès
Abstract excerpt
HLA-G is a non-classical major histocompatibility complex class Ib molecule. Its expression has been described in various cancer types, including ovarian cancer. HLA-G molecule has been implicated in immune escape and in progression of ovarian tumor cells. Our goal was to assess if total soluble (s)HLA-G molecules or HLA-G5 and sHLA-G1 isoforms could be considered as circulating ovarian tumor biomarkers, we...
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