Article
BRAFV600E Gene Mutation in Colonic Adenocarcinomas. Immunohistochemical Detection Using Tissue Microarray and Clinicopathologic Characteristics: An 86 Case Series.
Applied immunohistochemistry & molecular morphology : AIMM - 1 Feb 2016
Boulagnon Camille, Dudez Oriane, Beaudoux Olivia, Dalstein Véronique, Kianmanesh Reza, Bouché Olivier, Diebold Marie-Danièle
Abstract excerpt
The detection of BRAF mutation in colorectal cancer has several clinical applications: enabling the discrimination between sporadic and Lynch syndrome-related colorectal carcinoma, and providing warning of a poorer prognosis. Few immunohistochemical studies using whole-tissue tumor section staining have recently been performed on colorectal cancer. The aim of this study was to evaluate the detection of BRAF...
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