Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mucin phenotype and genetic alterations in non-V600E BRAF-mutated colorectal cancer.

Human pathology - 1 Mar 2024

Ozeki Hikaru, Shimada Yoshifumi, Nakano Mae, Kondo Shuhei, Ohashi Riuko, Miwa Yamato, Yamai Daisuke, Matsumoto Akio, Abe Kaoru, Tajima Yosuke, Ichikawa Hiroshi, Sakata Jun, Takii Yasumasa, Sugai Mika, Nagai Takahiro, Ling Yiwei, Okuda Shujiro, Wakai Toshifumi

Abstract excerpt

Colorectal cancer (CRC) is a heterogeneous disease that develops through stepwise accumulation of genetic alterations and progresses via several distinct pathways. However, the tumorigenesis of CRCs with BRAF non-V600E mutations remains unclear. Here, we aimed to elucidate the tumorigenesis of CRCs with BRAF non-V600E mutations, focusing on differences in mucin phenotype and genetic alterations between CRCs with...

Topics

Humans
Proto-Oncogene Proteins B-raf
Carcinogenesis
Cell Transformation, Neoplastic
Mutation
Phenotype
Colorectal Neoplasms

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 38423222
DOI: 10.1016/j.humpath.2024.02.009

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mucin phenotype and genetic alterations in non-V600E BRAF-mutated colorectal cancer.PMID 38423222Read ↗

Colorectal carcinomas with mucinous differentiation are associated with high frequent mutation of KRAS or BRAF mutations, irrespective of quantity of mucinous component.Semantic proximity Read ↗

BRAF-mutated colorectal adenocarcinomas: Pathological heterogeneity and clinical implications.Semantic proximity Read ↗

Molecular genetic analysis of colorectal carcinoma with an aggressive extraintestinal immunohistochemical phenotype.Semantic proximity Read ↗

Non-V600 BRAF Mutations Define a Clinically Distinct Molecular Subtype of Metastatic Colorectal Cancer.Semantic proximity Read ↗

Clinicopathological Significance of BRAFV600E Mutation in Colorectal Cancer: An Updated Meta-AnalysisSemantic proximity Read ↗

BRAF Mutation in Colorectal Cancer: An UpdateSemantic proximity Read ↗

The molecular background of mucinous carcinoma beyond MUC2Semantic proximity Read ↗

Targeted Therapy for Colorectal Cancers With Non-V600 BRAF Mutations: Perspectives for Precision OncologySemantic proximity Read ↗

Next generation sequencing targeted detection of somatic mutations in patients with mucinous adenocarcinoma of the appendix.Semantic proximity Read ↗

The heterogeneous clinical and pathological landscapes of metastatic Braf-mutated colorectal cancerSemantic proximity Read ↗

Clinicopathologic Features and Prognosis of BRAF Mutated Colorectal Cancer PatientsSemantic proximity Read ↗

Frequency and Clinicopathological Characteristics of Patients With KRAS/BRAF Double-Mutant Colorectal Cancer: An In Silico Study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.