Article
The impact of comparative genomic hybridization/single-nucleotide polymorphism microarray in risk stratification of pediatric acute lymphoblastic leukemia.
Pediatric blood & cancer - 1 Sept 2024
Gourmel Antoine, Perrault Héloïse, Colaiacovo Marie-Laure, Laramée Louise, Rozendaal Marieke, Bittencourt Henrique, Laverdière Caroline, Champagne Josette, Cellot Sonia, Silverman Lewis B, Lemyre Emmanuelle, Maftei Catalina, Mathonnet Géraldine, Tihy Frédérique, Pelland-Marcotte Marie-Claude, Léveillé France, Tran Thai Hoa
Abstract excerpt
BACKGROUND: The objective of this study is to assess the concordance and added value of combined comparative genomic hybridization plus single-nucleotide polymorphism microarray (CGH/SNP) analyses in pediatric acute lymphoblastic leukemia (ALL) risk stratification compared to conventional cytogenetic methods. PROCEDURE: This is a retrospective study that included patients aged 1-18 years diagnosed with de novo...
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