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Article

Genetic targets in pediatric acute lymphoblastic leukemia.

Advances in experimental medicine and biology - 1 Jan 2013

Gowda Chandrika, Dovat Sinisa

Abstract excerpt

Acute leukemia represents 31% of all cancers diagnosed in children and 80% of it is of Lymphoblastic type. Multiple genetic lesions in the hematopoietic progenitor cells prior to or during differentiation to B and T cell lead to development of leukemia. There are several subtypes of Acute Leukemia based on chromosome number changes, the presence of certain translocations and gene mutations, each of which has...

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PMID: 23288647
DOI: 10.1007/978-1-4614-6176-0_15

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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