Article
Genomic profiling of adult acute lymphoblastic leukemia by single nucleotide polymorphism oligonucleotide microarray and comparison to pediatric acute lymphoblastic leukemia.
Haematologica - 1 Sept 2010
Okamoto Ryoko, Ogawa Seishi, Nowak Daniel, Kawamata Norihiko, Akagi Tadayuki, Kato Motohiro, Sanada Masashi, Weiss Tamara, Haferlach Claudia, Dugas Martin, Ruckert Christian, Haferlach Torsten, Koeffler H Phillip
Abstract excerpt
BACKGROUND: Differences in survival have been reported between pediatric and adult acute lymphoblastic leukemia. The inferior prognosis in adult acute lymphoblastic leukemia is not fully understood but could be attributed, in part, to differences in genomic alterations found in adult as compared to in pediatric acute lymphoblastic leukemia. DESIGN AND METHODS: We compared two different sets of high-density single...
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