Article
Impact of dietary deviation on disease progression and gut microbiome composition in lupus-prone SNF1 mice.
Clinical and experimental immunology - 1 Aug 2015
Johnson B M, Gaudreau M-C, Al-Gadban M M, Gudi R, Vasu C
Abstract excerpt
Environmental factors, including microbes and diet, play a key role in initiating autoimmunity in genetically predisposed individuals. However, the influence of gut microflora in the initiation and progression of systemic lupus erythematosus (SLE) is not well understood. In this study, we have examined the impact of drinking water pH on immune response, disease incidence and gut microbiome in a spontaneous mouse...
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