Article
Dietary tryptophan and genetic susceptibility expand gut microbiota that promote systemic autoimmune activation
2024-01-20
Abstract excerpt
<h4>Summary</h4> Tryptophan modulates disease activity and the composition of microbiota in the B6. Sle1.Sle2.Sle3 (TC) mouse model of lupus. To directly test the effect of tryptophan on the gut microbiome, we transplanted fecal samples from TC and B6 control mice into germ-free or antibiotic-treated non-autoimmune B6 mice that were fed with a high or low tryptophan diet. The recipient mice with TC microbiota an...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- cce9cb7c-69d6-5d60-9efb-518f38098301
- DOI
- 10.1101/2024.01.16.575942