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Gut microbiota promote the inflammatory response in the pathogenesis of systemic lupus erythematosus

1 Aug 2019

Abstract excerpt

OBJECTIVES: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease whose onset and progression are affected by genetic and environmental factors. The purpose of this study is to identify the influence of gut microbiota in the pathogenesis of SLE, and to investigate the mechanism involved. METHODS: Fecal microbiota from C57/BL6 mice and SLE prone mice were examined using next-generation sequencing...

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PMID: 31370803
DOI: 10.1186/s10020-019-0102-5

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