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Gut Microbiota in Human Systemic Lupus Erythematosus and a Mouse Model of Lupus

1 Dec 2017

Abstract excerpt

ABSTRACT Gut microbiota dysbiosis has been observed in a number of autoimmune diseases. However, the role of the gut microbiota in systemic lupus erythematosus (SLE), a prototypical autoimmune disease characterized by persistent inflammation in multiple organs of the body, remains elusive. Here we report the dynamics of the gut microbiota in a murine lupus model, NZB/W F1, as well as intestinal dysbiosis in a...

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PMID: 29196292
DOI: 10.1128/aem.02288-17

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