Temporal evolution of the microbiome, immune system, and epigenome with disease progression in ALS mice

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) is a terminal neurodegenerative disease. Genetic predisposition, epigenetic changes, aging, and accumulated life-long environmental exposures are known ALS risk factors. The complex and dynamic interplay between these pathological influences play a role in disease onset and progression. Recently, the gut microbiome has also been implicated in ALS development. Additionally,...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Amyotrophic Lateral Sclerosis Research
• Share to Epigenetics and DNA Methylation
• Share to Histone Deacetylase Inhibitors Research