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Article

TET2 and CSMD1 genes affect SBP response to hydrochlorothiazide in never-treated essential hypertensives

18 Feb 2015

Abstract excerpt

BACKGROUND: Thiazide diuretics have been recommended as a first-line antihypertensive treatment, although the choice of 'the right drug in the individual essential hypertensive patient' remains still empirical. Essential hypertension is a complex, polygenic disease derived from the interaction of patient's genetic background with the environment. Pharmacogenomics could be a useful tool to pinpoint gene variants...

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Share to Genetic Associations and Epidemiology
Share to Hormonal Regulation and Hypertension
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PMID: 25695618
DOI: 10.1097/hjh.0000000000000541

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